Building on previous research showing that cancer cells send signals to the immune system to avoid being attacked, Stanford scientists have engineered new molecules that are highly proficient at neutralizing those signals.
The molecules dramatically increase the effectiveness of certain existing cancer therapies and may open up other avenues for treating cancer using patients’ own immune systems.
Image: Christopher Garcia, Ph.D.
Funding: This work was supported by the National Cancer Institute, the National Institute of Diabetes and Digestive and Kidney Diseases, the Stanford Medical Scientist Training Program, the School of Medicine’s SPARK program, the Deutsche Forschungsgemeinschaft, the Joseph & Laurie Lacob Gynecologic/Ovarian Cancer Fund, the Virginia and D.K. Ludwig Fund for Cancer Research and the Howard Hughes Medical Institute.